Biomimetic bone-periosteum scaffold for spatiotemporal regulated innervated bone regeneration and remedy of osteosarcoma | Journal of Nanobiotechnology


  • Liu Okay, Liao Y, Zhou Z, Zhang L, Jiang Y, Lu H, Xu T, Yang D, Gao Q, Li Z, Tan S, Cao W, Chen F, Li G. Photothermal-triggered immunogenic nanotherapeutics for optimizing osteosarcoma remedy by synergizing innate and adaptive immunity. Biomaterials. 2022;282:121383.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhao Y, Peng X, Xu X, Wu M, Solar F, Xin Q, Zhang H, Zuo L, Cao Y, Xia Y, Luo J, Ding C, Li J. Chitosan based mostly photothermal scaffold combating in opposition to bone tumor-related issues: recurrence, an infection, and defects. Carbohydr Polym. 2023;300:120264.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chu X, Zhang L, Li Y, He Y, Zhang Y, Du C. NIR Responsive Doxorubicin-Loaded Hole Copper Ferrite @ Polydopamine for synergistic Chemodynamic/Photothermal/Chemo-Remedy. Small. 2023;19:e2205414.

    Article 
    PubMed 

    Google Scholar
     

  • Yang Q, Yin H, Xu T, Zhu D, Yin J, Chen Y, Yu X, Gao J, Zhang C, Chen Y, Gao Y. Engineering 2D Mesoporous Silica@MXene-Built-in 3D-Printing scaffolds for Combinatory Osteosarcoma Remedy and NO-Augmented bone regeneration. Small. 2020;16:e1906814.

    Article 
    PubMed 

    Google Scholar
     

  • Marrella A, Lee TY, Lee DH, Karuthedom S, Syla D, Chawla A, Khademhosseini A, Jang HL. Engineering vascularized and innervated bone biomaterials for improved skeletal tissue regeneration. Mater In the present day (Kidlington). 2018;21:362–76.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang X, Li S, Zhang S, Gupta A, Zhang C, Wang L. The neural system regulates bone homeostasis by way of mesenchymal stem cells: a translational method. Theranostics. 2020;10:4839–50.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang Z, Wang F, Huang X, Solar H, Xu J, Qu H, Yan X, Shi W, Teng W, Jin X, Shao Z, Zhang Y, Zhao S, Wu Y, Ye Z, Yu X. Engineered sensory nerve guides Self-Adaptive Bone Therapeutic by way of NGF-TrkA signaling pathway. Adv Sci (Weinh). 2023;10:e2206155.

    Article 
    PubMed 

    Google Scholar
     

  • Ma YX, Jiao Okay, Wan QQ, Li J, Liu MY, Zhang ZB, Qin W, Wang KY, Wang YZ, Tay FR, Niu LN. Silicified collagen scaffold induces semaphorin 3A secretion by sensory nerves to enhance in-situ bone regeneration. Bioact Mater. 2022;9:475–90.

    CAS 
    PubMed 

    Google Scholar
     

  • Li Z, Meyers CA, Chang L, Lee S, Li Z, Tomlinson R, Hoke A, Clemens TL. James A W. Fracture restore requires TrkA signaling by skeletal sensory nerves. J Clin Investig. 2019;129:5137–50.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Leitão L, Neto E, Conceição F, Monteiro A, Couto M, Alves CJ, Sousa DM, Lamghari M. Osteoblasts are inherently programmed to repel sensory innervation. Bone Res. 2020;8:20.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek D, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL. NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of growing endochondral bone. Cell Rep. 2016;16:2723–35.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tomlinson RE, Li Z, Li Z, Minichiello L, Riddle RC, Venkatesan A, Clemens TL. NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical hundreds in mice. Proc Natl Acad Sci U S a. 2017;114:E3632–41.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang H, Zhang M, Zhai D, Qin C, Wang Y, Ma J, Zhuang H, Shi Z, Wang L, Wu C. Polyhedron-Like Biomaterials for Innervated and Vascularized Bone Regeneration. Adv Mater. 2023:e2302716.

  • Yu Y, Wang Y, Zhang W, Wang H, Li J, Pan L, Han F, Li B. Biomimetic periosteum-bone substitute composed of preosteoblast-derived matrix and hydrogel for big segmental bone defect restore. Acta Biomater. 2020;113:317–27.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhang D, Tan J, Xu R, Du H, Xie J, Peng F, Liu X. Collaborative design of MgO/FeO(x) nanosheets on Titanium: combining remedy with regeneration. Small. 2023;19:e2204852.

    Article 
    PubMed 

    Google Scholar
     

  • Zhang H, Qin C, Zhang M, Han Y, Ma J, Wu J, Yao Q, Wu C. Calcium silicate nanowires-containing multicellular bioinks for 3D bioprinting of neural-bone constructs. Nano In the present day. 2022;46:101584.

    Article 
    CAS 

    Google Scholar
     

  • Li W, Miao W, Liu Y, Wang T, Zhang Y, Wang W, Lu D, Zhou X, Jiao X, Jia X. Bioprinted constructs that mimic the ossification middle microenvironment for focused innervation in bone regeneration. Adv Funct Mater. 2022;32:2109871.

    Article 
    CAS 

    Google Scholar
     

  • Wang L, Pang Y, Tang Y, Wang X, Zhang D, Zhang X, Yu Y, Yang X, Cai Q. A biomimetic piezoelectric scaffold with sustained Mg2 + launch promotes neurogenic and angiogenic differentiation for enhanced bone regeneration. Bioact Mater. 2023;25:399–414.

    CAS 
    PubMed 

    Google Scholar
     

  • Xu C, Chang Y, Wu P, Liu Okay, Dong X, Nie A, Mu C, Liu Z, Dai H, Luo Z. Two-dimensional‐Germanium Phosphide‐Strengthened Conductive and Biodegradable Hydrogel scaffolds improve spinal twine Harm Restore. Adv Funct Mater. 2021;31:2104440.

    Article 
    CAS 

    Google Scholar
     

  • Xu Y, Xu C, He L, Zhou J, Chen T, Ouyang L, Guo X, Qu Y, Luo Z, Duan D. Stratified-structural hydrogel integrated with magnesium-ion-modified black phosphorus nanosheets for selling neuro-vascularized bone regeneration. Bioact Mater. 2022;16:271–84.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gong B, Zhang X, Zahrani AA, Gao W, Ma G, Zhang L, Xue J. Neural tissue engineering: from bioactive scaffolds and in situ monitoring to regeneration. Explor (Beijing). 2022;2:20210035.

    CAS 

    Google Scholar
     

  • Chen P, Xu C, Wu P, Liu Okay, Chen F, Chen Y, Dai H, Luo Z. Wirelessly powered Electrical-Stimulation based mostly on biodegradable 3D Piezoelectric Scaffolds promotes the spinal twine Harm Restore. ACS Nano. 2022;16:16513–28.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Tan MH, Xu XH, Yuan TJ, Hou X, Wang J, Jiang ZH, Peng LH. Self-powered sensible patch promotes pores and skin nerve regeneration and sensation restoration by delivering biological-electrical indicators in program. Biomaterials. 2022;283:121413.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wan X, Zhao Y, Li Z, Li L. Rising polymeric electrospun fibers: from structural variety to software in versatile bioelectronics and tissue engineering. Explor (Beijing). 2022;2:20210029.

    CAS 

    Google Scholar
     

  • Varga M, Morvan J, Diorio N, Buyuktanir E, Harden J, West JL, Jákli A. Direct piezoelectric responses of soppy composite fiber mats. Appl Phys Lett. 2013;102:153903.

    Article 

    Google Scholar
     

  • Ribeiro HB, Ramos S, Seixas L, De Matos C, Pimenta MA. Edge phonons in layered orthorhombic GeS and GeSe monochalcogenides. Phys Rev B. 2019;100:94301.

    Article 
    CAS 

    Google Scholar
     

  • Zhai W, Lai Q, Chen L, Zhu L, Wang ZL. Versatile piezoelectric nanogenerators based mostly on P (VDF–TrFE)/GeSe nanocomposite movies. Acs Appl Electron Mater. 2020;2:2369–74.

    Article 
    CAS 

    Google Scholar
     

  • Chai Z, Zhang W, Clima S, Hatem F, Degraeve R, Diao Q, Zhang JF, Freitas P, Marsland J, Fantini A. Biking induced metastable degradation in GeSe Ovonic threshold switching selector. Ieee Electron System Lett. 2021;42:1448–51.

    Article 
    CAS 

    Google Scholar
     

  • Li X, Wang Y, Chen Y, Zhou P, Wei Okay, Wang H, Wang J, Fang H, Zhang S. Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition. Biomaterials. 2020;257:120253.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang Y, Hao H, Liu H, Wang Y, Li Y, Yang G, Ma J, Mao C, Zhang S. Selenite-releasing bone Mineral nanoparticles Retard Bone Tumor Progress and enhance wholesome tissue features in vivo. Adv Healthc Mater. 2015;4:1813–8.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Liu SC, Mi Y, Xue DJ, Chen YX, He C, Liu X, Hu JS, Wan LJ. Investigation of bodily and digital properties of GeSe for photovoltaic purposes. Adv Electron Mater. 2017;3:1700141.

    Article 

    Google Scholar
     

  • Duan C, Yu M, Xu J, Li B, Zhao Y, Kankala RK. Overcoming Most cancers Multi-drug Resistance (MDR): causes, mechanisms, nanotherapeutic options, and challenges. Biomed Pharmacother. 2023;162:114643.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bian D, Zhou W, Deng J, Liu Y, Li W, Chu X, Xiu P, Cai H, Kou Y, Jiang B, Zheng Y. Improvement of magnesium-based biodegradable metals with dietary hint aspect germanium as orthopaedic implant purposes. Acta Biomater. 2017;64:421–36.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhou N, Lengthy H, Wang C, Yu L, Zhao M, Liu X. Analysis progress on the organic actions of selenium polysaccharides. Meals Funct. 2020;11:4834–52.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Dang W, Yi Okay, Ju E, Jin Y, Xu Y, Wang H, Chen WC, Wang Okay, Wang Y, Tao Y, Li M. 3D printed Bioceramic scaffolds as a Common Therapeutic platform for synergistic remedy of Osteosarcoma. Acs Appl Mater Interfaces. 2021;13:18488–99.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Xu C, Xia Y, Zhuang P, Liu W, Mu C, Liu Z, Wang J, Chen L, Dai H, Luo Z. FePSe3-Nanosheets-Built-in Cryogenic-3D-Printed multifunctional calcium phosphate scaffolds for synergistic remedy of Osteosarcoma. Small. 2023;19:2303636.

    Article 
    CAS 

    Google Scholar
     

  • Han Y, Liu C, Chen B, Fu C, Kankala RK, Wang S, Chen A. Orchestrated tumor apoptosis (Cu2+) and bone tissue calcification (Ca2+) by hierarchical Copper/Calcium-ensembled bioactive silica for osteosarcoma remedy. Chem Eng J. 2022;435:134820.

    Article 
    CAS 

    Google Scholar
     

  • Ren Okay, Zhu M, Track W, Lv S, Xia M, Yong W, Lu Y, Ji Z, Track Z. Electrical switching properties and structural traits of GeSe-GeTe movies. Nanoscale. 2018;11:1595–603.

    Article 

    Google Scholar
     

  • Yap WC, Yang Z, Mehboudi M, Yan J, Barraza-Lopez S, Zhu W. Layered materials GeSe and vertical GeSe/MoS2 p-n heterojunctions. Nano Res. 2018;11:420–30.

    Article 
    CAS 

    Google Scholar
     

  • Zeng J, Goldfeld D, Xia Y. A Plasmon-assisted optofluidic (PAOF) system for measuring the Photothermal Conversion Efficiencies of Gold Nanostructures and Controlling an Electrical change. Angew Chem Int Ed. 2013;52:4169–73.

    Article 
    CAS 

    Google Scholar
     

  • Manikandan M, Hasan N, Wu H. Platinum nanoparticles for the photothermal remedy of Neuro 2A most cancers cells. Biomaterials. 2013;34:5833–42.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Perez RA, Mestres G. Position of pore dimension and morphology in musculo-skeletal tissue regeneration. Mater Sci Eng C Mater Biol Appl. 2016;61:922–39.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pérez-Hernández M, Del PP, Mitchell SG, Moros M, Stepien G, Pelaz B, Parak WJ, Gálvez EM, Pardo J, de la Fuente JM. Dissecting the molecular mechanism of apoptosis throughout photothermal remedy utilizing gold nanoprisms. ACS Nano. 2015;9:52–61.

    Article 
    PubMed 

    Google Scholar
     

  • Fan T, Yan L, He S, Hong Q, Ai F, He S, Ji T, Hu X, Ha E, Zhang B, Li Z, Zhang H, Chen X, Hu J. Biodistribution, degradability and clearance of 2D supplies for his or her biomedical purposes. Chem Soc Rev. 2022;51:7732–51.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Chen L, Chen C, Chen W, Li Okay, Chen X, Tang X, Xie G, Luo X, Wang X, Liang H, Yu S. Biodegradable black phosphorus nanosheets mediate particular supply of hTERT siRNA for synergistic Most cancers remedy. Acs Appl Mater Interfaces. 2018;10:21137–48.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Rao F, Wang Y, Zhang D, Lu C, Cao Z, Sui J, Wu M, Zhang Y, Pi W, Wang B, Kou Y, Wang X, Zhang P, Jiang B. Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic issue and vascular endothelial progress issue restore long-distance sciatic nerve defects in rats. Theranostics. 2020;10:1590–603.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ning C, Zhou Z, Tan G, Zhu Y, Mao C. Electroactive polymers for tissue regeneration: developments and views. Prog Polym Sci. 2018;81:144–62.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tang G, Dong X, Huang X, Huang XJ, Liu H, Wang Y, Ye WC, Shi L. A pure diarylheptanoid promotes neuronal differentiation by way of activating ERK and PI3K-Akt dependent pathways. Neuroscience. 2015;303:389–401.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhong J. RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal growth, operate and dysfunction. Biol Chem. 2016;397:215–22.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ghosh A, Greenberg ME. Calcium signaling in neurons: molecular mechanisms and mobile penalties. Science. 1995;268:239–47.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Qian Y, Zhao X, Han Q, Chen W, Li H, Yuan W. An built-in multi-layer 3D-fabrication of PDA/RGD coated graphene loaded PCL nanoscaffold for peripheral nerve restoration. Nat Commun. 2018;9:323.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Salhotra A, Shah HN, Levi B, Longaker MT. Mechanisms of bone growth and restore. Nat Rev Mol Cell Biol. 2020;21:696–711.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jones RE, Salhotra A, Robertson KS, Ransom RC, Foster DS, Shah HN, Quarto N, Wan DC, Longaker MT. Skeletal stem cell-Schwann Cell Circuitry in Mandibular Restore. Cell Rep. 2019;28:2757–66.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wan QQ, Qin WP, Ma YX, Shen MJ, Li J, Zhang ZB, Chen JH, Tay FR, Niu LN, Jiao Okay. Crosstalk between bone and nerves inside bone. Adv Sci (Weinh). 2021;8:2003390.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, Barro C, Kappos L, Comabella M, Fazekas F, Petzold A, Blennow Okay, Zetterberg H, Kuhle J. Neurofilaments as biomarkers in neurological issues. Nat Rev Neurol. 2018;14:577–89.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Mi J, Xu J, Yao Z, Yao H, Li Y, He X, Dai B, Zou L, Tong W, Zhang X, Hu P, Ruan YC, Tang N, Guo X, Zhao J, He J, Qin L. Implantable Electrical stimulation at dorsal Root ganglions accelerates osteoporotic fracture Therapeutic by way of Calcitonin Gene-related peptide. Adv Sci (Weinh). 2022;9:2103005.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ye L, Xu J, Mi J, He X, Pan Q, Zheng L, Zu H, Chen Z, Dai B, Li X, Pang Q, Zou L, Zhou L, Huang L, Tong W, Li G, Qin L. Biodegradable magnesium mixed with distraction osteogenesis synergistically stimulates bone tissue regeneration by way of CGRP-FAK-VEGF signaling axis. Biomaterials. 2021;275:120984.

    Article 

    Google Scholar
     

  • Xu C, Xia Y, Zhuang P, Liu W, Mu C, Liu Z, Wang J, Chen L, Dai H, Luo Z. FePSe(3) -Nanosheets-Built-in Cryogenic-3D-Printed multifunctional calcium phosphate scaffolds for synergistic remedy of Osteosarcoma. Small. 2023:e2303636.

  • Blattmann C, Thiemann M, Stenzinger A, Roth EK, Dittmar A, Witt H, Lehner B, Renker E, Jugold M, Eichwald V, Weichert W, Huber PE, Kulozik AE. Institution of a patient-derived orthotopic osteosarcoma mouse mannequin. J Transl Med. 2015;13:136.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang X, Li Y, Huang L, Jiang XW, Jiang L, Dong H, Wei Z, Li J, Hu W. Brief-Wave Close to-Infrared Linear Dichroism of two-Dimensional Germanium Selenide. J Am Chem Soc. 2017;139:14976–82.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ren X, Liu W, Zhou H, Wei J, Mu C, Wan Y, Yang X, Nie A, Liu Z, Yang X, Luo Z. Biodegradable 2D GeP nanosheets with excessive photothermal conversion effectivity for multimodal most cancers theranostics. Chem Eng J. 2022;431:134176.

    Article 
    CAS 

    Google Scholar
     

  • Related Articles

    LEAVE A REPLY

    Please enter your comment!
    Please enter your name here

    Latest Articles